The HCRN registry is a huge database collecting detailed information on children at the HCRN centers. The information is entered in real time as children are treated and continuously checked for accuracy. This makes it a very valuable resource. Dr Jay Riva-Cambrin is the lead investigator for this project and at the American Society of Pediatric Neurosurgeons in February he presented the first analysis of the data. Dr Riva-Cambrin and our Ph.D. biostatistician, Richard Holubkov, looked at the factors that predict shunt failure in 1036 children after the first shunt insertion. They found that children under 6 months of age and children who had their shunt inserted with an endoscope had a higher chance of shunt failure. In addition, children with a congenital heart problem were at increased risk. Even more interesting was the list of factors that did not alter the risk of failure. This included: the cause of hydrocephalus, the type of valve used (including programmable valves), the use of ultrasound or guidance during the surgery, and surgeon volume. These important findings are now being prepared for publication and they will help us advise families and guide our future research.
Archive for the ‘Research’ Category
By John Kestle, Monday, July 8th, 2013
By John Kestle, Tuesday, January 29th, 2013
At the last HCRN meeting (November 2012), we discussed ETV/CPC (Endoscopic third ventriculostomy with choroid plexus coagulation). This procedure was pioneered by Dr. Ben Warf (Boston Children’s Hospital) during his time in Uganda and he was a guest at the November HCRN meeting. He reviewed the technique and his data and we discussed the possibility of doing an HCRN study on this procedure. We felt that the first important step in that direction was for some HCRN members to gain additional experience with the technique. Dr. Warf kindly offered to train some HCRN investigators in Uganda. He makes periodic trips there to treat children with hydrocephalus at the Cure Children’s Hospital of Uganda. This month, Dr. Riva-Cambrin from the Salt Lake City HCRN center, Dr. Whitehead from the Texas HCRN center and Dr. Rozzelle from the Birmingham, Alabama HCRN center are in Uganda working with Dr. Warf. Other investigators will be doing the same later this spring. We hope this experience will allow us to study this innovative procedure in the near future.